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Article

UV fingerprints predominate in the PTCH mutation spectra of basal cell carcinomas independent of clinical phenotype.

The Journal of investigative dermatology - 1 Dec 2007

Heitzer Ellen, Lassacher Anita, Quehenberger Franz, Kerl Helmut, Wolf Peter

Abstract excerpt

Basal cell carcinoma (BCC) shows a wide interpatient variation in lesion accrual. To determine whether certain tumorigenic fingerprints and potentially predisposing patched (PTCH) tumor suppressor single-nucleotide polymorphisms (SNPs) are distributed differently among sporadic BCC patients, we compared the PTCH mutation spectra in early-onset BCC (first lesion at age < 35 years), regular BCC (first lesion at age...

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Share to Carcinoma, Basal Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

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Source

Identifiers

PMID: 17597822
DOI: 10.1038/sj.jid.5700923

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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