Article

Profile of basal cell carcinoma mutations and copy number alterations - focus on gene-associated noncoding variants

2021-06-24

Abstract excerpt

<h4>ABSTRACT</h4> Basal cell carcinoma (BCC) of the skin is the most common cancer in humans, characterized by the highest mutation rate among cancers, and is mostly driven by mutations in genes involved in the hedgehog pathway. To date, almost all BCC genetic studies have focused exclusively on protein-coding sequences; therefore, the impact of noncoding variants on the BCC genome is unrecognized. In this study,...

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Literature Corpus work: cd0eb7b5-db2a-5584-b0db-b9ee4a30be1f
DOI: 10.1101/2021.06.24.449728

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