Article
Hierarchical organization of the human cell from a cancer coessentiality network
2018-05-23
Abstract excerpt
Genetic interactions mediate the emergence of phenotype from genotype. Systematic survey of genetic interactions in yeast showed that genes operating in the same biological process have highly correlated genetic interaction profiles, and this observation has been exploited to infer gene function in model organisms. Systematic surveys of digenic perturbations in human cells are also highly informative, but are not...
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Identifiers and source
- Literature Corpus work
- eb81e4e3-174d-5234-be1a-e41338074a68
- DOI
- 10.1101/328880