Article
High-resolution mapping of cancer cell networks using co-functional interactions
2018-07-16
Abstract excerpt
Powerful new technologies for perturbing genetic elements have expanded the study of genetic interactions in model systems ranging from yeast to human cell lines. However, technical artifacts can confound signal across genetic screens and limit the immense potential of parallel screening approaches. To address this problem, we devised a novel PCA-based method for eliminating these artifacts and bolstering sensitiv...
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Identifiers and source
- Literature Corpus work
- 7eeaff03-3768-5d77-9701-910e473e8d38
- DOI
- 10.1101/369751