Article

Single-cell RNA editing defines clinically relevant cellular states in chronic myelomonocytic leukemia

2026-03-18

Abstract excerpt

<h4>Background</h4> Chronic myelomonocytic leukemia (CMML) is a clinically heterogeneous myeloid malignancy with limited therapeutic options and suboptimal risk stratification. Although single-cell RNA sequencing has refined disease classification through gene expression profiling, post-transcriptional mechanisms—particularly adenosine-to-inosine (A-to-I) RNA editing—remain unexplored at single-cell resolution. W...

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Literature Corpus work: ea3fe5a6-d2a6-5ea0-b37b-c4937eec1e72
DOI: 10.64898/2026.03.15.711339

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