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Article

RNA editing contributes to epitranscriptome diversity in chronic lymphocytic leukemia.

Leukemia - 1 Apr 2021

Gassner Franz J, Zaborsky Nadja, Buchumenski Ilana, Levanon Erez Y, Gatterbauer Matthias, Schubert Maria, Rauscher Stefanie, Hebenstreit Daniel, Nadeu Ferran, Campo Elias, Egle Alexander, Greil Richard, Geisberger Roland

Abstract excerpt

RNA editing-primarily conversion of adenosine to inosine (A > I)-is a widespread posttranscriptional mechanism, mediated by Adenosine Deaminases acting on RNA (ADAR) enzymes to alter the RNA sequence of primary transcripts. Hence, in addition to somatic mutations and alternative RNA splicing, RNA editing can be a further source for recoding events. Although RNA editing has been detected in many solid cancers and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32728184
DOI: 10.1038/s41375-020-0995-6
PMCID: PMC8024191

Genes

ADAR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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