Article

Multiscale RNA editing analysis reveals cell type–specific regulatory programs across disease states in acute myeloid leukemia

2026-02-06

Abstract excerpt

<h4>Background</h4> Acute myeloid leukemia (AML) is characterized by marked cellular heterogeneity and immune dysregulation. Adenosine-to-inosine (A-to-I) RNA editing, primarily catalyzed by ADAR and ADARB1, represents an important post-transcriptional regulatory mechanism, yet its condition- and cell type–specific landscape in AML remains poorly defined, particularly at single-cell resolution. <h4>Methods</h4>...

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Literature Corpus work: 4860ae11-7b79-50a4-b963-a69be8c7a9d9
DOI: 10.64898/2026.02.04.703797

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