Article

A Glycolysis-Fatty Acid Metabolic Axis Shapes Human Tfh Cell Function

2026-04-03

Abstract excerpt

Follicular helper T (Tfh) cells orchestrate germinal centre-derived humoral immunity by providing essential help to B cells. Despite their key role in humoral immunity, the metabolic processes that guide Tfh differentiation and functions in human remain poorly understood. In this study, we used a human ex vivo Tfh differentiation model to investigate how key metabolic pathways influence Tfh cell differentiation an...

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Literature Corpus work: e978c2f8-50b0-5c57-ba5e-4dc1819c1363
DOI: 10.64898/2026.04.01.715763

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