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Distinct bioenergetic features of human invariant natural killer T (iNKT) cells enable retained functions in nutrient-deprived states

2021-04-29

Abstract excerpt

<h4>ABSTRACT</h4> Invariant natural killer T (iNKT) cells comprise a unique subset of lymphocytes that are primed for activation and possess innate NK-like functional features. Currently, iNKT cell-based immunotherapies remain in early clinical stages, and little is known about the ability of these cells to survive and retain effector functions within the solid tumor microenvironment (TME) long-term. In conventio...

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Literature Corpus work
99d1e849-6a88-5136-92e7-0bf1f6eb127b
DOI
10.1101/2021.04.29.442021
Open publication

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Distinct bioenergetic features of human invariant natural killer T (iNKT) cells enable retained functions in nutrient-deprived statesDOI 10.1101/2021.04.29.442021
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