Article

Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state

2014-06-12

Abstract excerpt

<h4>Summary</h4> The conserved Musashi (Msi) family of RNA binding proteins are expressed in stem/progenitor and cancer cells, but mostly absent from differentiated cells, consistent with a role in cell state regulation. We found that Msi genes are rarely mutated but frequently overexpressed in human cancers, and associated with an epithelial-luminal cell state. Using ribosome footprint profiling and RNA-seq anal...

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Literature Corpus work: e9437b2f-76cd-5354-8b26-dbe65ac4a12c
DOI: 10.1101/006270

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