Article

Single-cell multi-omics decodes regulatory programs during development of mouse secondary palate

2022-11-03

Abstract excerpt

<h4>SUMMARY</h4> The abnormal perturbation in gene regulation during palatogenesis may lead to cleft palate, a major congenital birth defect in humans and mice. However, a comprehensive multi-omic map of the developing secondary palate at single-cell resolution is lacking. In this study, we performed single-cell multiome sequencing and profiled chromatin accessibility and gene expression simultaneously within the...

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Literature Corpus work: a2868ca4-f748-51ea-bca1-8b44796d1349
DOI: 10.1101/2022.11.02.514609

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