Article

Staufen2 modulates the temporal dynamics of human neurogenesis <i>in vitro</i>

2025-10-02

Abstract excerpt

RNA-binding proteins (RBPs) play a central role in post-transcriptional regulation during brain development, yet their specific functions in coordinating human neural lineage decisions remain poorly understood. Here, we investigate for the first time the role of the double-stranded RBP Staufen2 (STAU2) in human neurogenesis. Characterization of STAU2 knockout iPSC derived cells using scRNA-seq shows that loss of S...

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Literature Corpus work: 384fd7b4-011b-528f-b3d3-342508d3fe1e
DOI: 10.1101/2025.10.02.679988

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