Article

RNA binding protein Musashi1 interacts with the viral genomic RNA and restricts SARS-CoV-2 infection by repressing translation

2024-10-02

Abstract excerpt

Musashi RNA binding proteins are important post-transcriptional regulators of stem cell homeostasis and are known to be involved in viral infections. However, their role in SARS-CoV-2 infection remains largely unknown. Using computational studies, in vivo RNA immunoprecipitation and biochemical assays, here, we establish that Musashi 1 (Msi1) interacts with viral genomic RNA through direct binding to the SARS-CoV-...

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Literature Corpus work: 17d8fbf9-ea62-55d9-8cd8-ef24a56c4ed5
DOI: 10.1101/2024.09.29.615653

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RNA binding protein Musashi1 interacts with the viral genomic RNA and restricts SARS-CoV-2 infection by repressing translationDOI 10.1101/2024.09.29.615653Read

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