Article
The RNA-binding protein Musashi is required intrinsically to maintain stem cell identity.
Proceedings of the National Academy of Sciences of the United States of America - 30 May 2006
Siddall Nicole A, McLaughlin Eileen A, Marriner Neisha L, Hime Gary R
Abstract excerpt
A key goal of regenerative medicine is an understanding of the genetic factors that define the properties of stem cells. However, stem cell research in mammalian tissue has been hampered by a paucity of stem cell-specific markers. Although increasing evidence suggests that members of the Musashi (Msi) family of RNA-binding proteins play important functions in progenitor cells, it remains unclear whether there is...
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