Article

Genetic background and mistranslation frequency determine the impact of mistranslating tRNA <sup>Ser</sup> <sub>UGG</sub>

2022-03-24

Abstract excerpt

<h4>ABSTRACT</h4> Transfer RNA variants increase the frequency of mistranslation, the mis-incorporation of an amino acid not specified by the “standard” genetic code, to frequencies approaching 10% in yeast and bacteria. Cells cope with these variants by having multiple copies of each tRNA isodecoder and through pathways that deal with proteotoxic stress. In this study, we define the genetic interactions of the g...

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Literature Corpus work: e6fe388a-d352-550b-a6ac-d52d72519504
DOI: 10.1101/2022.03.22.485345

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Genetic background and mistranslation frequency determine the impact of mistranslating tRNA <sup>Ser</sup> <sub>UGG</sub>DOI 10.1101/2022.03.22.485345Read

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