Article

Mistranslating tRNA variants impact the proteome and phosphoproteome of <i>Saccharomyces cerevisiae</i>

2025-09-18

Abstract excerpt

<h4>ABSTRACT</h4> Transfer RNAs (tRNAs) ensure accurate decoding of the genetic code. However, mutations in tRNAs can lead to mis-incorporation of an amino acid that differs from the genetic message in a process known as mistranslation. As mistranslating tRNAs modify how the genetic message is decoded, they have potential as therapeutic tools for diseases caused by nonsense and missense mutations. Despite this, t...

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Literature Corpus work: 0674ac04-fce7-5ea6-9c01-2d3b845e6322
DOI: 10.1101/2025.09.15.676438

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