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Article

Mistranslating tRNA identifies a deleterious S213P mutation in the Saccharomyces cerevisiaeeco1-1 allele.

Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Oct 2020

Zhu Yanrui, Berg Matthew D, Yang Phoebe, Loll-Krippleber Raphaël, Brown Grant W, Brandl Christopher J

Abstract excerpt

Mistranslation occurs when an amino acid not specified by the standard genetic code is incorporated during translation. Since the ribosome does not read the amino acid, tRNA variants aminoacylated with a non-cognate amino acid or containing a non-cognate anticodon dramatically increase the frequency of mistranslation. In a systematic genetic analysis, we identified a suppression interaction between...

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PMID: 32476470
DOI: 10.1139/bcb-2020-0151

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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