Article

Mistranslating tRNA identifies a deleterious S213P mutation in the <i>Saccharomyces cerevisiae eco1-1</i> allele

2020-04-09

Abstract excerpt

<h4>ABSTRACT</h4> Mistranslation occurs when an amino acid not specified by the standard genetic code is incorporated during translation. Since the ribosome does not read the amino acid, tRNA variants aminoacylated with a non-cognate amino acid or containing a non-cognate anticodon dramatically increase the frequency of mistranslation. In a systematic genetic analysis, we identified a suppression interaction betw...

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Literature Corpus work: 4131e19a-f62d-5027-ab9c-46963f791d61
DOI: 10.1101/2020.04.08.031922

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