Article
Mistranslation: from adaptations to applications.
Biochimica et biophysica acta. General subjects - 1 Nov 2017
Hoffman Kyle S, O'Donoghue Patrick, Brandl Christopher J
Abstract excerpt
BACKGROUND: The conservation of the genetic code indicates that there was a single origin, but like all genetic material, the cell's interpretation of the code is subject to evolutionary pressure. Single nucleotide variations in tRNA sequences can modulate codon assignments by altering codon-anticodon pairing or tRNA charging. Either can increase translation errors and even change the code. The frozen accident...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
