Article

Two distinct chromatin modules regulate proinflammatory gene expression

2024-08-06

Abstract excerpt

Various mechanisms have been proposed to explain gene activation and co-regulation, including enhancer-promoter interactions via chromatin looping and the enrichment of transcription factors into hubs or condensates. However, these conclusions often stem from analyses of individual loci, and genome-wide studies exploring mechanistic differences with coupled gene expression are lacking. In this study, we dissected...

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Literature Corpus work: e53e595b-900c-54dc-835d-0ff738dba065
DOI: 10.1101/2024.08.03.606159

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