Article

Functional Inference of Gene Regulation using Single-Cell Multi-Omics

2021-07-28

Abstract excerpt

Cells require coordinated control over gene expression when responding to environmental stimuli. Here, we apply scATAC-seq and scRNA-seq in resting and stimulated human blood cells. Collectively, we generate ∼91,000 single-cell profiles, allowing us to probe the cis -regulatory landscape of immunological response across cell types, stimuli and time. Advancing tools to integrate multi-omic data, we develop FigR -...

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Literature Corpus work: 1ce9c6cd-25a9-533b-b3fb-b44926fa91e0
DOI: 10.1101/2021.07.28.453784

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