Article

Inflammatory stress-mediated chromatin changes underlie dysfunction in endothelial cells

2023-10-16

Abstract excerpt

<h4>ABSTRACT</h4> Inflammatory stresses underlie endothelial dysfunction and contribute to the development of chronic cardiovascular disorders such as atherosclerosis and vascular fibrosis. The initial transcriptional response of endothelial cells to pro-inflammatory cytokines such as TNF-alpha is well established. However, very few studies uncover the effects of inflammatory stresses on chromatin architecture. W...

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Literature Corpus work: 372cd250-f27b-5dc5-b209-369eda6216db
DOI: 10.1101/2023.10.11.561959

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