Article

Comparing bulk and single-cell methodologies and models to profile gene expression, chromatin accessibility and regulatory links in endothelial cells treated with TNFα

2026-03-16

Abstract excerpt

<h4>ABSTRACT</h4> Genome-wide association studies (GWAS) have identified thousands of non-coding variants associated with complex traits and diseases. However, it remains challenging to pinpoint the causal genes that are regulated by associated genetic variants. Connecting causal non-coding variants with genes can rely on methods that identify direct physical interactions (e.g. chromosome conformation capture) or...

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Literature Corpus work: fa2c51cf-60a4-52ac-9998-fa7b647d6c6f
DOI: 10.64898/2026.03.13.711357

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