Article

Nucleolar Condensation Orchestrates rRNA-dependent Mobility and Spatiotemporally Enriches rDNA-binding of Human Chromatin Remodeler BRG1

2026-04-04

Abstract excerpt

<h4>ABSTRACT</h4> As key regulators of genome access via nucleosome translocation/ejection, SWI/SNF chromatin remodeling complexes share a core ATPase/translocase subunit, BRG1, central to their activity. Despite recent discovery of spatially clustered intranuclear “hotspots” where various SWI/SNF remodelers preferentially bind, the mechanistic driving force underlying such heterogeneous organization remains uncl...

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Literature Corpus work: e43d7e97-7cfd-5d94-8d90-5aca26f7d896
DOI: 10.64898/2026.04.03.716269

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