Article

Liquid-like transcription condensates locally constrain chromatin in living human cells

2025-07-09

Abstract excerpt

The organization and dynamics of chromatin play important roles in transcriptional regulation. The transcription machinery is known to constrain chromatin dynamics. Recently, transcription condensates formed via liquid–liquid phase separation (LLPS) or other mechanisms have emerged as key regulators of gene expression. What is the physical nature of such condensates in the cell? Do they interact with and constrain...

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Literature Corpus work: a1774174-9ad9-5c8f-aa36-364fc9fe2f36
DOI: 10.1101/2025.07.05.663270

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