Article

Integrative transcriptome analysis of malignant pleural mesothelioma reveals a clinically relevant immune-based classification

2020-08-15

Abstract excerpt

<h4>Background</h4> Malignant pleural mesothelioma (MPM) is a rare and aggressive neoplasia affecting the lung mesothelium. Immune checkpoint inhibitors (ICI) in MPM have not been extremely successful, likely due to poor identification of suitable candidate patients for the therapy. We aimed to identify cellular immune fractions associated with clinical outcome and classify MPM patients based on their immune conte...

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Literature Corpus work: e2fe86ac-b056-5acb-926a-8d2cdae7db3d
DOI: 10.1101/2020.08.14.20174789

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