Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Single-cell analysis of diverse immune phenotypes in malignant pleural effusion

18 Nov 2021

Abstract excerpt

Abstract The complex interactions among different immune cells have important functions in the development of malignant pleural effusion (MPE). Here we perform single-cell RNA sequencing on 62,382 cells from MPE patients induced by non-small cell lung cancer to describe the composition, lineage, and functional states of infiltrating immune cells in MPE. Immune cells in MPE display a number of transcriptional...

Source

Identifiers

PMID: 34795282
DOI: 10.1038/s41467-021-27026-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-cell analysis of diverse immune phenotypes in malignant pleural effusionPMID 34795282Read ↗

Multi-omic profiling of pleural effusions: a reservoir-incubator for non-invasive insights into tumor heterogeneitySemantic proximity Read ↗

Single-Cell Transcriptomics of Immune Cells Reveal Diversity and Exhaustion Signatures in Non-Small-Cell Lung CancerSemantic proximity Read ↗

Dissecting transcriptional heterogeneity in multiple primary lung cancer by single cell RNA sequencingSemantic proximity Read ↗

Single cell view of tumor microenvironment gradients in pleural mesotheliomaSemantic proximity Read ↗

Single-Cell View of Tumor Microenvironment Gradients in Pleural MesotheliomaSemantic proximity Read ↗

Single‐cell RNA sequencing analysis reveals transcriptional heterogeneity of multiple primary lung cancerSemantic proximity Read ↗

Single-cell RNA sequencing reveals heterogeneous tumor and immune cell populations in early-stage lung adenocarcinomas harboring EGFR mutations.Semantic proximity Read ↗

Single-cell RNA sequencing reveals potential therapeutic targets in the tumor microenvironment of lung squamous cell carcinomaSemantic proximity Read ↗

Landscape and dynamics of single tumor and immune cells in early and advanced‐stage lung adenocarcinomaSemantic proximity Read ↗

Liquid Biopsy Based Single‐Cell Transcriptome Profiling Characterizes Heterogeneity of Disseminated Tumor Cells from Lung AdenocarcinomaSemantic proximity Read ↗

Single-cell and spatial transcriptomics analysis of non-small cell lung cancerSemantic proximity Read ↗

Single-cell RNA sequencing demonstrates the molecular and cellular reprogramming of metastatic lung adenocarcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.