Article

Pharmacological AMP-activated protein kinase activation suppresses low glucose-dependent macrophage migration inhibitory factor release from macrophages

2023-10-19

Abstract excerpt

<h4>Aims/hypothesis</h4> Acute hypoglycemia promotes pro-inflammatory cytokine production, increasing risk for cardiovascular events in diabetes. AMP-activated protein kinase (AMPK) is regulated by and influences production of pro-inflammatory cytokines. We tested the mechanistic role of AMPK in low glucose induced changes in the pro-inflammatory cytokine macrophage migration inhibitory factor (MIF), which is ele...

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Literature Corpus work: e26d2f4d-b221-5cef-b1c2-d743ffb7e11b
DOI: 10.1101/2023.10.16.562445

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