Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart.

Nature - 31 Jan 2008

Miller Edward J, Li Ji, Leng Lin, McDonald Courtney, Atsumi Toshiya, Bucala Richard, Young Lawrence H

Abstract excerpt

Understanding cellular response to environmental stress has broad implications for human disease. AMP-activated protein kinase (AMPK) orchestrates the regulation of energy-generating and -consuming pathways, and protects the heart against ischaemic injury and apoptosis. A role for circulating hormones such as adiponectin and leptin in the activation of AMPK has received recent attention. Whether local autocrine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to AMP-Activated Protein Kinases
Share to Antigens, Differentiation, B-Lymphocyte

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class II

Share to Hypoxia

Share to Macrophage Migration-Inhibitory Factors

Share to Multienzyme Complexes

Share to Myocardial Ischemia

Share to Myocardial Reperfusion Injury

Source

Identifiers

PMID: 18235500
DOI: 10.1038/nature06504

Genes

MIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart.PMID 18235500Read ↗

Impaired macrophage migration inhibitory factor-AMP-activated protein kinase activation and ischemic recovery in the senescent heart.Semantic proximity Read ↗

Pharmacological AMP-activated protein kinase activation suppresses low glucose-dependent macrophage migration inhibitory factor release from macrophagesSemantic proximity Read ↗

AMP-activated protein kinase: a core signalling pathway in the heart.Semantic proximity Read ↗

α1AMPK deletion in myelomonocytic cells induces a pro-inflammatory phenotype and enhances angiotensin II-induced vascular dysfunction.Semantic proximity Read ↗

Microarray expression analysis in delayed cardioprotection: the effect of exercise, AICAR, or metformin and the possible role of AMP-activated protein kinase (AMPK).Semantic proximity Read ↗

AMP-Activated Protein Kinase α1 in Macrophages Promotes Collateral Remodeling and Arteriogenesis in Mice In Vivo.Semantic proximity Read ↗

AMPK: An Epigenetic Landscape ModulatorSemantic proximity Read ↗

Metformin directly suppresses atherosclerosis in normoglycaemic mice via haematopoietic adenosine monophosphate-activated protein kinase.Semantic proximity Read ↗

AMP-activated protein kinase (AMPK) control of fatty acid and glucose metabolism in the ischemic heart.Semantic proximity Read ↗

Targeting AMPK for cardiac protection: opportunities and challenges.Semantic proximity Read ↗

AMPK activation reduces the number of atheromata macrophages in ApoE deficient mice.Semantic proximity Read ↗

Antithrombin up-regulates AMP-activated protein kinase signalling during myocardial ischaemia/reperfusion injury.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.