Article

Notch signalling influences cell fate decisions and HOX gene induction in axial progenitors

2023-06-16

Abstract excerpt

<h4>ABSTRACT</h4> The generation of the post-cranial embryonic body relies on the coordinated production of spinal cord neurectoderm and presomitic mesoderm cells from neuromesodermal progenitors (NMPs). This process is orchestrated by pro-neural and pro-mesodermal transcription factors that are co-expressed in NMPs together with Hox genes, which are critical for axial allocation of NMP derivatives. NMPs reside i...

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Literature Corpus work: e06f17da-40db-51d8-9043-85570dc67cf8
DOI: 10.1101/2023.06.16.545269

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