Article

Comparative human embryo-mapping reveals neural bias of neuromesodermal progenitors in stem cell axial elongation models

2026-03-09

Abstract excerpt

Elongation of the human body axis is driven by the coordinated differentiation of neural and mesodermal tissues. Pluripotent stem cell-based organoid models recapitulate key aspects of axial elongation, but how they relate to the regional organization of axial development in the embryo remains unclear. Here, we map scRNA-seq from twelve stem cell-based axial organoids to a stage-matched embryo. Integrated transcri...

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Literature Corpus work: fc60d025-cfce-5593-963a-cb0f632caee8
DOI: 10.64898/2026.03.06.710064

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