Article

Reconstituting human somitogenesis <i>in vitro</i>

2022-06-03

Abstract excerpt

The segmented body plan of vertebrates is established during somitogenesis, a well-studied process in model organisms, but remains largely elusive in humans due to ethical and technical limitations. Despite recent advances with pluripotent stem cell (PSC)-based approaches 1–5 , a system that robustly recapitulates human somitogenesis in both space and time remains missing. Here, we introduce a PSC-derived mesoder...

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Literature Corpus work: fc45a2f2-fb22-52e3-bf34-7ab23f0025fb
DOI: 10.1101/2022.06.03.494621

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