Article

WNT/β-CATENIN modulates the axial identity of ES derived human neural crest

2019-01-08

Abstract excerpt

<h4>ABSTRACT</h4> The WNT/β-CATENIN pathway is critical for neural crest (NC) formation. However, the effects of the magnitude of the signal remains poorly defined. Here we evaluate the consequences of WNT magnitude variation in a robust model of human NC formation. This model is based on human embryonic stem cells induced by WNT signaling through the small molecule CHIR9902. In addition to its known effect on NC...

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Literature Corpus work: bce5db04-e250-594b-b87a-d64d5e439927
DOI: 10.1101/514570

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