Article

Early anteroposterior regionalisation of human neural crest is shaped by a pro-mesodermal factor

2021-09-24

Abstract excerpt

The neural crest (NC) is an important multipotent embryonic cell population and its impaired specification leads to various developmental defects, often in an anteroposterior (A-P) axial level-specific manner. The mechanisms underlying the correct A-P regionalisation of human NC cells remain elusive. Recent studies have indicated that trunk NC cells, the presumed precursors of the childhood tumour neuroblastoma, a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a2fa58b8-5e25-524b-bb83-decfa7ddfeb2
DOI: 10.1101/2021.09.24.461516

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Early anteroposterior regionalisation of human neural crest is shaped by a pro-mesodermal factorDOI 10.1101/2021.09.24.461516Read

WNT/β-CATENIN modulates the axial identity of ES derived human neural crestSemantic proximity Read

Human axial progenitors generate trunk neural crest cellsSemantic proximity Read

WNT/β-CATENIN modulates the axial identity of ES derived human neural crestSemantic proximity Read

Notch signalling influences cell fate decisions and HOX gene induction in axial progenitorsSemantic proximity Read

Hijacking of Embryonic Programs by Neural Crest-Derived Neuroblastoma: From Physiological Migration to Metastatic DisseminationSemantic proximity Read

Rostrocaudal patterning and neural crest differentiation of human pre-neural spinal cord progenitors in vitroSemantic proximity Read

A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal aberrationsSemantic proximity Read

A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal aberrationsSemantic proximity Read

Posterior specification of multi-lineage axial assembloids from human pluripotent stem cellsSemantic proximity Read

Axial Elongation of Caudalized Human Organoids Mimics Neural Tube DevelopmentSemantic proximity Read

Mechanisms involved in selecting and maintaining neuroblastoma cancer stem cell populations, and perspectives for therapeutic targetingSemantic proximity Read

Defining the signalling determinants of a posterior ventral spinal cord identity in human neuromesodermal progenitor derivativesSemantic proximity Read