Article

Posterior axis formation requires <i>Dlx5/Dlx6</i> expression at the neural plate border

2018-10-04

Abstract excerpt

<h4>ABSTRACT</h4> Neural tube defects (NTDs), one of the most common birth defects in human, present a multifactorial etiology with a poorly defined genetic component. The Dlx5 and Dlx6 bigenic cluster encodes two evolutionary conserved homeodomain transcription factors, which are necessary for proper vertebrate development. It has been shown that Dlx5/6 genes are essential for anterior neural tube closure, ho...

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Literature Corpus work: 8e40f45c-6f25-513b-9726-cfaf25edfd3c
DOI: 10.1101/435321

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