Article

Posterior specification of multi-lineage axial assembloids from human pluripotent stem cells

2024-08-30

Abstract excerpt

<h4>ABSTRACT</h4> Elongation of the posterior body axis is driven by multi-potent neuromesodermal progenitors (NMPs), which both self-renew and simultaneously generate neural tube, neural crest, and presomitc mesoderm lineages at successive anterior posterior (A-P) levels. The ensuing diversification of these three NMP lineages is remarkably extensive, and also essential for an immense range of clinically importa...

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Literature Corpus work: a7020e1e-f0cf-5b00-93bd-0728e5c4775b
DOI: 10.1101/2024.08.29.610410

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