Article

Unbiased phosphoproteomics analysis unveils modulation of insulin signaling by extramitotic CDK1 kinase activity in human myotubes

2023-07-01

Abstract excerpt

<h4>SUMMARY</h4> Sensitivity and plasticity of insulin signaling and glucose uptake in skeletal muscle depends on determinants such as genetic variation and obesity. We collected muscle biopsies and isolated myoblasts from a multi-ethnic cohort of lean South Asians (N=10), lean Chinese (N=10), and obese Chinese (N=10), and analysed the proteome and phosphoproteome dynamics in terminally differentiated myotubes af...

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Literature Corpus work: e06cfe2c-eec5-5dfd-98ee-8d53eda14a0c
DOI: 10.1101/2023.06.30.547176

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Unbiased phosphoproteomics analysis unveils modulation of insulin signaling by extramitotic CDK1 kinase activity in human myotubesDOI 10.1101/2023.06.30.547176Read

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