Article

Interplay of PAK1 and CAMKII in Pancreatic Beta Cell Insulin Secretion

2025-03-11

Abstract excerpt

<h4>Background: </h4> /Objectives: Type 2 diabetes mellitus (T2DM) is a major global health challenge, primarily driven by insulin resistance and beta-cell dysfunction. This study investigated the roles of p21-activated kinase 1 (PAK1) and calci-um/calmodulin-dependent protein kinase II (CAMKII) in insulin secretion, aiming to elucidate their involvement in this process and their implications in T2DM pathophysi-ol...

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Literature Corpus work: 6cf07975-a5bc-577d-a6ff-1deb43b626f7
DOI: 10.20944/preprints202503.0714.v1

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