Article

The Multifaceted Role of S6K1 in Cellular Regulation and Disease: Structural Insights, Isoform-Specific Functions, and Therapeutic Potential

2024-08-30

Abstract excerpt

S6K1 (ribosomal protein S6 kinase beta-1) is a serine/threonine kinase integral to regulating protein synthesis, gene expression, and metabolic homeostasis. Its structural complexity, including multiple isoforms and a unique kinase domain, enables diverse functions across cellular contexts. This review examines the intricate structure of S6K1, its tissue-specific expression, and subcellular localization, emphasizi...

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Literature Corpus work: e9bacd47-ff85-55c2-9437-b25770503c52
DOI: 10.22541/au.172501394.49993134/v1

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