Article

Protective role of <i>Pten</i> downregulation in Huntington’s Disease models

2024-04-01

Abstract excerpt

Huntington’s disease (HD) is a dominantly inherited neurodegenerative disorder that stems from the expansion of CAG repeats within the coding region of the Huntingtin gene. Currently, there exists no effective therapeutic intervention that can prevent the progression of the disease. Our investigation aims to identify a novel genetic modifier with therapeutic potential. We employ transgenic flies containing Htt93Q...

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Literature Corpus work: df7f7d3f-af87-5619-b14e-1df76574a2f7
DOI: 10.1101/2024.03.28.587147

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