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<i>Drosophila</i> egg-derived tyrosine phosphatase (EDTP): a novel target for improved survivorship to prolonged anoxia and cellular protein aggregates

2018-03-10

Abstract excerpt

Drosophila egg-derived tyrosine phosphatase (EDTP), a lipid phosphatase that removes 3-position phosphate at the inositol ring, has dual functions in the oogenesis and the muscle performance during adult stages. A mammalian homologous gene MTMR14 , which encodes the myotubularin-related protein 14, negatively regulates autophagy. Mutation of EDTP/MTMR14 , however, causes at least three deleterious consequences:...

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Literature Corpus work
a6fd2ef6-51a3-5cda-b9d5-959afb03bcca
DOI
10.1101/279885
Open publication

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