Article
Mouse models of polyglutamine diseases in therapeutic approaches: review and data table. Part II.
Molecular neurobiology - 1 Oct 2012
Switonski Pawel M, Szlachcic Wojciech J, Gabka Agnieszka, Krzyzosiak Wlodzimierz J, Figiel Maciej
Abstract excerpt
Mouse models of human diseases are created both to understand the pathogenesis of the disorders and to find successful therapies for them. This work is the second part in a series of reviews of mouse models of polyglutamine (polyQ) hereditary disorders and focuses on in vivo experimental therapeutic approaches. Like part I of the polyQ mouse model review, this work is supplemented with a table that contains data...
Topics
- Animals
- Databases as Topic
- Disease Models, Animal
- Humans
- Mice
- Molecular Targeted Therapy
- Neurodegenerative Diseases
- Peptides
- Phenotype