Article

Pharmacological inhibition of PTEN rescues dopaminergic neurons by attenuating apoptotic and neuroinflammatory signalling events

2022-07-18

Abstract excerpt

<title>Abstract</title> <p>Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by a selective degeneration of dopaminergic neurons in the ventral mid-brain of humans called substantia nigra. This results in an irreversible and debilitating motor dysfunction. Though both genetic and idiopathic factors are implicated in the disease etiology, idiopathic PD comprise the majority of clin...

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Literature Corpus work: e01699bb-2edb-5f54-ac37-465a1f2d235a
DOI: 10.21203/rs.3.rs-1785484/v1

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