Article

Purinergic Signaling Participates in a Transition Between Functional States of Reactive Microglia and Controls Astrocyte-Driven Neuroinflammation in the Model of Trimethyltin-Induced Neurodegeneration

2020-12-29

Abstract excerpt

<title>Abstract</title> <p>BackgroundThe present study aims to explore the involvement of purinergic signaling in the rodent model of hippocampal degeneration induced by trimethyltin (TMT), which results in behavioral and neurological dysfunction similar to Alzheimer’s disease. Our study has provided novel evidence that TMT induced extracellular depositions of amyloid β, which might be the cause of the well-defin...

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Literature Corpus work: dddbeee3-1740-5203-874c-f89973bb5a97
DOI: 10.21203/rs.3.rs-135545/v1

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Purinergic Signaling Participates in a Transition Between Functional States of Reactive Microglia and Controls Astrocyte-Driven Neuroinflammation in the Model of Trimethyltin-Induced NeurodegenerationDOI 10.21203/rs.3.rs-135545/v1Read

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