Article

Rapid recycling of glutamate transporters on the astroglial surface

2020-11-09

Abstract excerpt

<h4>ABSTRACT</h4> Glutamate uptake by high-affinity astroglial transporters confines excitatory transmission to the synaptic cleft. The efficiency of this mechanism depends on the transporter dynamics in the astrocyte membrane, which remains poorly understood. Here, we visualise the main glial glutamate transporter GLT1 by generating its functional pH-sensitive fluorescent analogue, GLT1-SEP. Combining FRAP-based...

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Literature Corpus work: dd5ea112-50da-566e-a2ea-94dae209d0bc
DOI: 10.1101/2020.11.08.373233

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