Article

Bestrophin-1 (BEST1) in the Central Nervous System from Mechanism to Disease

2026-05-13

Abstract excerpt

Bestrophin-1 (BEST1) was first linked to retinal disease, yet in the central nervous system BEST1 has been assigned a distinct functional scope spanning transmitter permeation, circuit set point control, and injury responses. In this mini-review, current evidence is examined for BEST1 as a neurotransmitter-gated anion channel, with emphasis placed on structural and biophysical studies that have clarified gating, p...

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Literature Corpus work: 41f9a1e4-9999-5fa4-9e02-dbad08760513
DOI: 10.20944/preprints202605.0854.v1

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