Article

Relationship Between Neuroendocrine and Immune Gene Expression in Small Cell Lung Cancer

2020-08-04

Abstract excerpt

<title>Abstract</title> <p>Small cell lung cancer (SCLC) is classified as a high-grade neuroendocrine (NE) tumor, but a subset of SCLC has been termed “variant” due to the loss of NE characteristics. In this study, we computed NE scores for patient-derived SCLC cell lines and xenografts, as well as human tumors. We aligned NE properties with transcription factor-defined molecular subtypes. Then we investigated th...

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Literature Corpus work: dab3da6b-220a-516d-a7d3-62e2dac16ab7
DOI: 10.21203/rs.3.rs-50416/v1

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