Article

Small Cell Lung Cancer Neuroendocrine Subtypes are Associated with Different Immune Microenvironment and Checkpoint Molecule Distribution

2020-02-03

Abstract excerpt

<h4>ABSTRACT</h4> Small cell lung cancer (SCLC) has recently been sub-categorized into neuroendocrine (NE)- high and NE-low subtypes showing ‘immune desert’ and ‘immune oasis’ phenotypes, respectively. We aimed to characterize the immune cell localization and the microenvironment according to immune checkpoints and NE subtypes in human SCLC tissue samples at the protein level. In this cross-sectional study, we in...

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Literature Corpus work: 27c3e32a-2d26-5248-a161-312fe1ab6871
DOI: 10.1101/2020.02.02.930305

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