Article

Relationship Between Neuroendocrine and Immune Gene Expression in Small Cell Lung Cancer

2020-07-29

Abstract excerpt

<h4>ABSTRACT</h4> Small cell lung cancer (SCLC) is classified as a high-grade neuroendocrine (NE) tumor, but a subset of SCLC has been termed “variant” due to the loss of NE characteristics. In this study, we computed NE scores for patient-derived SCLC cell lines and xenografts, as well as human tumors. We aligned NE properties with transcription factor-defined molecular subtypes. Then we investigated the differe...

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Literature Corpus work: eb0f1fac-7760-55de-b361-8912522349bd
DOI: 10.1101/2020.07.28.225763

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