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Integrated Molecular and Clinical Characterization of Pulmonary Large Cell Neuroendocrine Carcinoma

2025-05-16

Abstract excerpt

<title>Abstract</title> <p>Pulmonary large cell neuroendocrine carcinoma (LCNEC) is a rare, aggressive lung tumor marked by significant molecular heterogeneity. In a study of 590 patients across two independent cohorts, we observed comparable overall survival across treatment regimens (chemotherapy, chemoimmunotherapy, immunotherapy) without unexpected adverse events. Genomic analysis identified distinct NSCLC-li...

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Literature Corpus work
b61f6dce-f83a-55ca-8ff4-74d8328ec728
DOI
10.21203/rs.3.rs-6639680/v1
Open publication

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